Comments on: The DNA Transistor and the implications for personalized medicine http://asmarterplanet.com/blog/2009/10/dna-transistor.html Just another weblog Mon, 15 Mar 2010 22:42:15 -0700 http://wordpress.org/?v=2.8.4 hourly 1 By: Boyd Steere http://asmarterplanet.com/blog/2009/10/dna-transistor.html#comment-10847 Boyd Steere Mon, 12 Oct 2009 20:27:55 +0000 http://asmarterplanet.com/?p=2691#comment-10847 Wow. Would love to see the raw signal data from this and train an ensemble of MLP artificial neural nets to predict base sequence under different conditions of voltage, current, solvent, buffer, conductivity etc. Even if there isn't a global solution for the best possible prediction, there's probably a pretty good local one in or near the accessible experimental data space, or a gradient of performance to suggest a direction to move in. Crossing my fingers that the conditions could be optimized in real time to tune the detector along the continuum between random and highly-repetitive GC-rich regions. Sounds like fun! Good luck! Wow. Would love to see the raw signal data from this and train an ensemble of MLP artificial neural nets to predict base sequence under different conditions of voltage, current, solvent, buffer, conductivity etc. Even if there isn’t a global solution for the best possible prediction, there’s probably a pretty good local one in or near the accessible experimental data space, or a gradient of performance to suggest a direction to move in.

Crossing my fingers that the conditions could be optimized in real time to tune the detector along the continuum between random and highly-repetitive GC-rich regions.

Sounds like fun! Good luck!

]]> By: Better than real http://asmarterplanet.com/blog/2009/10/dna-transistor.html#comment-10669 Better than real Fri, 09 Oct 2009 17:07:24 +0000 http://asmarterplanet.com/?p=2691#comment-10669 <strong>IBM DNA Transistor...</strong> Your personal DNA sequencing  co-processor is not far away from now. IBM taking big leaps to make it happen. This technology will totally reshape the landscape of medicine and how drugs will be prescribed in the near future. ...... IBM DNA Transistor…

Your personal DNA sequencing  co-processor is not far away from now. IBM taking big leaps to make it happen.
This technology will totally reshape the landscape of medicine and how drugs will be prescribed in the near future.

……

]]> By: IBM Research aims to build Nanoscale DNA Sequencer to help drive down cost of Personalized Genetic Analysis | Health Informer http://asmarterplanet.com/blog/2009/10/dna-transistor.html#comment-10472 IBM Research aims to build Nanoscale DNA Sequencer to help drive down cost of Personalized Genetic Analysis | Health Informer Tue, 06 Oct 2009 08:39:51 +0000 http://asmarterplanet.com/?p=2691#comment-10472 [...] For an ongoing conversation on this research project, visit the Smarter Planet blog: http://asmarterplanet.com/blog/2009/10/dna-transistor.html [...] [...] For an ongoing conversation on this research project, visit the Smarter Planet blog: http://asmarterplanet.com/blog/2009/10/dna-transistor.html [...]

]]> By: IBM Research Aims to Build Nanoscale DNA Sequencer to Help Drive Down Cost of Personalized Genetic Analysis | Free Press Release http://asmarterplanet.com/blog/2009/10/dna-transistor.html#comment-10460 IBM Research Aims to Build Nanoscale DNA Sequencer to Help Drive Down Cost of Personalized Genetic Analysis | Free Press Release Tue, 06 Oct 2009 04:48:01 +0000 http://asmarterplanet.com/?p=2691#comment-10460 [...] View video: View animation: For an ongoing conversation on this research project, visit the Smarter Planet blog: http://asmarterplanet.com/blog/2009/10/dna-transistor.html [...] [...] View video: View animation: For an ongoing conversation on this research project, visit the Smarter Planet blog: http://asmarterplanet.com/blog/2009/10/dna-transistor.html [...]

]]>