Our group works on smarter healthcare project. Our task is to find all repetitive sequences in human and rat chromosomes. Those sequences are called ultra conserved elements (UCE) which highly preserved in genome, remaining unchanged for nearly 300 million years. By setting up our own Hadoop Cluster (one master node and seven data nodes), we can run Java MapReduce program on Large Scale Genome DataSet in short period of time. We designed and implemented our Java MapReduce program to obtain UCE and stored it to HBase.